Sports Bar- Miller's Ale House, O'Quigley's Irish Pub, McGuires (Irish also)
Seafood- Back Porch (right on beach); Acme Oyster House (In Baytown); Dewey Destin (on water, i've never been there though); AJs (In Harbor); Crab Trap (on Beach); Lucky Snapper
Pizza-HelenBack (In Oklaoosa Island, really nice view, it's a biker bar type place, great pizza and beer place), Ciao Bella, Jordano's
Mexican-Cantina Laredo
All I have for now, really can't go wrong with a lot of the seafood places around here, lots of good ones, just depends on the price range you want
No really great local steak places, just chains (outback and longhorn)...just trying to suggest the local type places
If you want a really great cheap fast good type mexican place, there's a place in Niceville (which is where actually I live, it's basically right next door to Destin) called Taco Town, great tacos for a cheap price (most expensive thing they have is like $4.00)