OU has three things going for them in this game:
1. The disrespect card (which has been powerful in past playoff games);
2. The fact the Grinch's D will be so fucked up and out of position in what it does that it might confuse Burrow for a while and throw off his timing; and
3. The fact that LSU's defense, while seemingly on the upswing, will still likely give up 30 points or more to OU.
All that said, I expect that OU's defense will sell out to pressure Burrow and that Burrow will destroy that first with a bunch of screens to Edwards-Helaire (he'll have massive YAC because OU sucks at tackling), next with timely scrambles, and then, once they've stopped selling out and he has more time, by bombing them over the top. LSU 49, OU 38.