TTUN has a great run game, but are one-dimensional and will struggle if they are trailing more than a TD late in the game. The defense has had most issues against the pass, and the DL and LBs are significantly better this year.
When healthy, OSU has been more consistent on offense and capable of dominant quarters against good defenses. Hayden is a huge boost when everyone else is hurt. The offense is completely different with any running game. TTUN's defense is strong up the middle but mediocre in the secondary.
Day & Wilson can be very creative when they want to be. This is more hopeful thinking, but I'd be surprised if they don't have some special packages and plays prepped. If they don't have that and more tempo to go to, I have to wonder what they've been doing all year.