Great thread topic rght here.
Two plays stand out to me this season:
-Arguably the biggest play in the Big Ten this year was the blocked FG and TD return at the end of the first half of the Michigan State game. That play propelled us to overcome the Penn State loss, get back in the game, beat up Drew Stanton, win the football game, and go on a big 6-game win streak that resulted in us sharing the Big Ten title and beat LLLLoyd...again. On the flip side, Michigan State, 4-1 at the time, never recovered, losing 5 of their last 6 to miss a bowl game.
-However my favorite play was probably Pittman's 67-yard burst against Minnesota. That play was also bubbling with significance: it blew the game open, helped the defense out in probably their only subpar game this season, and for Pittman, it was his first TD, a career day for yardage, he upstaged Maroney, the supposed Heisman candidate and self-proclaimed best back in the Big Ten, and it led to Pittman really dominating for the last several games of the season, when we really needed him, as he helped key the resurgence of the moribund offense to make us arguably the most explosive non-Rose Bowl team at the end of the year.