First: hope your day improvesAlright so... I couldn't find the original article from earlier this month but I think this is the study...
https://www.nature.com/articles/s41586-020-2550-z
Abstract in part:
Then in the course of searching for that, I found this:
https://www.cnn.com/2020/07/30/health/t-cells-coronavirus-study-wellness/index.html
So, I dunno how much you guys have been posting it here, but a lot of the immunity discussion has been shifting to T cells so, in the top one is a Singapore study where they ID that there are T-Cells in the population resistant to COVID 19, including SARS outbreak survivors who have memory T Cells from 17 years ago....
THen the next one is a study in Germany that puts the prevalence of said T-Cells at up to 35% (small sample size).
A good long while back I posted something similar about antibodies prevalence in Asia offering at least limited immunity based on exposure to SARS and other coronaviruses.
Now, why quote that along with the vaccine.
So, I think once the vaccine rolls out, the R naught will drop pretty quickly well below 1, because I think there's a pretty wide set of factors other than just 70% of people taking it...
So, first is, what is the population prevalence going to be by the end of the year... (I'm being kind of hypothetical here so if you don't like the numbers I'm good with that, not my point, big guesstimating)
If there are 7 million cases by the end of the year, CDC is saying we might only be catching 1 in 10 cases due to early issue, assyms etc... that by itself would be close to 20%... I think its high and we will see what more robust seroprevalence tests return, but at some point this part become important, even at 15% (These guys here estimate the undercount at a wonderfully wide 6 to 24 times... so if you're super optimistic 24 times 4 million is a big number https://www.the-scientist.com/news-...dy-in-us-shows-vast-covid-19-undercount-67762) And this data is old right now but that NYC test put it at 23%, now of course nearly everywhere else is a long way from the NYC infections per X people, and I think we'd prefer not to get there but... maybe slowly places catch up.
Then you have these TCell immunity factors - Is 35% right? I dunno, but even if its 15% - there's another big chunk (and largely the point here is there shouldn't be much, if any overlap between those groups)
But for giggles, let's say with those 2 things you already have 30% of people with some meaningful protection...that's a big deal.
(obviously there's a whole lot of "we don't know which people already have protection" that's going on, so you don't get to say, just give some other 30% the vaccine, but what you will have is 30% of the people who may not run to the front of the line, probably don't actually need it, and you get to 60% a lot quicker that way)
Anyway, I'm having a mostly rotten day so, if I don't respond to comments on this, nothing personal, I probably shouldn't be posting at all.
There are many studies discussing SARS-CoV-2 immune response; the one you cite is similar to what I was quoting, but not identical. Still, things appear to be looking up.
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